Intact protein quantification analysis provides information of the overall structure and properties of proteins without breaking them down into their constituent peptides or amino acids, which can be used to detect the molecular weight, structure, and modifications of proteins. Intact protein analysis is an essential method for evaluating biologics during manufacturing, enabling the assessment of purity and heterogeneity characteristics critical for lot release purposes.
INOMIXO's intact protein analysis service is tailored for precise measurement of intact protein quantification quality, facilitating confirmation of purified protein sequences and assessing the relative abundance of their isoforms. By employing a combination of liquid chromatography (LC) and time-of-flight mass spectrometry (TOF-MS), we conduct thorough characterization of intact protein quantification in solution.
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