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Intact protein quantification analysis provides information of the overall structure and properties of proteins without breaking them down into their constituent peptides or amino acids, which can be used to detect the molecular weight, structure, and modifications of proteins. Intact protein analysis is an essential method for evaluating biologics during manufacturing, enabling the assessment of purity and heterogeneity characteristics critical for lot release purposes.

INOMIXO Intact Protein Quantification Analysis Service

High Precision Measurement: INOMIXO's service is designed for precise measurement of intact protein quantification, ensuring accurate and reliable results. This precision is crucial for confirming the purity and sequence of proteins, which is essential for various applications in research and development.

Comprehensive Characterization: By employing a combination of liquid chromatography (LC) and time-of-flight mass spectrometry (TOF-MS), INOMIXO thoroughly characterizes intact proteins. This dual approach allows for detailed analysis, offering insights into the protein’s structure and composition.

Solution-Based Analysis: INOMIXO conducts protein quantification in solution, which mimics the natural environment of proteins. This approach ensures that the analysis is more representative of the protein's behavior in biological systems, leading to more relevant and applicable results.

Expertise and Experience: With a team of experienced professionals and state-of-the-art technology, INOMIXO guarantees high-quality service and support. Our expertise in protein analysis ensures that you receive accurate, detailed, and actionable data for your research needs.

Tailored Services:We understand that each project is unique. INOMIXO offers tailored CRO services to meet specific requirements, providing customized solutions that align with your research goals and objectives.

Intact Protein Analysis Project Workflow

Intact Protein Quantification

Intact Protein Analysis Application Display

Reasons to Select Intact Protein Quantification

Preservation of Native Structure: Intact protein quantification maintains the protein's native structure, providing accurate insights into its functional form and biological activity.

Comprehensive Analysis: This method detects post-translational modifications (PTMs) and isoforms, offering a complete view often missed in hydrolyzed protein analysis.

Accurate Mass Determination: It provides precise mass measurements, confirming the molecular weight and purity of intact proteins.

Simplified Sample Preparation: The method involves simpler sample preparation, saving time and reducing the risk of sample loss or contamination.

Reduced Risk of Artifacts: It minimizes artifacts introduced during hydrolysis, ensuring a more accurate representation of the protein's natural state.