INOMIXO, a proteomics service company, offers DIA proteomics, a high-throughput mass spectrometry technology. Compared to traditional DDA mode, DIA adopts a comprehensive scanning strategy, enabling the simultaneous detection of a large number of proteins. This technology is not restricted by pre-set target proteins, featuring higher sensitivity and dynamic range, capable of detecting proteins of lower abundance and accurately measuring the expression levels of high-abundance proteins. DIA proteomics has broad applications in biomedical research, such as discovering new biomarkers and studying protein modifications.
Proteomics service company INOMIXO's PTM proteomics technology focuses on investigating post-translational modifications of proteins. These modifications include phosphorylation, glycosylation, ubiquitination, etc., which play a crucial role in protein function and regulatory mechanisms. PTM proteomics, through advanced technologies such as mass spectrometry, can comprehensively analyze the modification states of proteins, revealing their key roles in cell signal transduction and disease occurrence.
Proteomics service company INOMIXO's 4D-DIA proteomics technology builds upon DIA technology by introducing ion mobility as an additional dimension, achieving higher precision and stability in quantifying the proteome. This technology is based on the timsTOF Pro2 platform, using PASEF (Parallel Accumulation Serial Fragmentation) technology, which allows near 100% ion utilization, greatly enhancing mass spectrometry scanning speed and detection sensitivity. 4D-DIA proteomics has vast applications in disease biomarker screening, drug development, and more.
Proteomics service company INOMIXO's TMT (Tandem Mass Tag) proteomics is an advanced technology for quantitative protein analysis. It uses chemically distinct tags to mark peptides, allowing for the simultaneous processing of multiple samples and mass spectrometry analysis. TMT technology offers high-throughput, high-sensitivity, and high-accuracy protein expression level comparison, making it a powerful tool in proteomics research. It significantly contributes to studying disease mechanisms, drug development, and biomarker screening.
Proteomics service company INOMIXO's proteomics services also include mass spectrometry-based protein identification. This service, utilizing advanced mass spectrometry instruments and data analysis methods, accurately identifies the identity, quantity, structure, and function of proteins present in samples. Protein identification is a key tool for deciphering the diversity and function of proteins in biological drugs, having crucial significance in drug research and development.